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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Cell Reactant: | Na+/H+ exchanger regulatory factor-1 PDZ domain (PDZ1) | ||
| Syringe Reactant: | BDBM228843 | ||
| Meas. Tech.: | Enzyme Inhibition | ||
| Entry Date: | 05/30/17 | ||
| ΔG°: | -26±1 (kJ/mole) | ||
| pH: | 8±0 | ||
| Log10Kb: | 7.61± 6.00 | ||
| Temperature: | 298.15±0 (K) | ||
| ΔH° : | -15.9±0.800 (kJ/mole) | ||
| ΔHobs: | n/a | ||
| Ionic Strength: | n/a | ||
| n/a | |||
| Protons Released: | n/a | ||
| ΔCp : | n/a | ||
| Stoich. Param.: | n/a | ||
| ΔS° : | 0.034±0.00300 (kJ/mole-K) | ||
| Comments: | n/a | ||
| Citation |  Mamonova, T; Zhang, Q; Chandra, M; Collins, BM; Sarfo, E; Bu, Z; Xiao, K; Bisello, A; Friedman, PA Origins of PDZ Binding Specificity. A Computational and Experimental Study Using NHERF1 and the Parathyroid Hormone Receptor. Biochemistry56:2584-2593 (2017) [PubMed] Article | ||
| More Info.: | Get all data from this article , ITC RUN data , Solution Info | ||
| Na+/H+ exchanger regulatory factor-1 PDZ domain (PDZ1) | |||
| Source: | n/a | ||
| Purity: | n/a | ||
| Prep. Method: | n/a | ||
| Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 [1-140] | ||
| Synonyms: | NHERF | NHERF1 | NHRF1_HUMAN | Na+/H+ exchanger regulatory factor-1 PDZ domain (PDZ1) | SLC9A3R1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 14899.03 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | PDZ1 domain of human NHERF1 (1-140 aa) | ||
| Residue: | 140 | ||
| Sequence: |
| ||
| BDBM228843 | |||
| Source: | n/a | ||
| Purity: | n/a | ||
| Prep. Method: | n/a | ||
| Name | BDBM228843 | ||
| Synonyms: | PTHRct-8 mutant (QAAWETVM) | QAAWETVM | ||
| Type | Small organic molecule | ||
| Emp. Form. | C41H62N10O13S | ||
| Mol. Mass. | 935.055 | ||
| SMILES | CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(C)C)C(O)=O |r| | ||
| Structure | 
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