Reaction Details | |||
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Target | Tyrosine-protein kinase receptor TYRO3 | ||
Ligand | BDBM308189 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Activity Assay | ||
IC50 | 30.0±n/a nM | ||
Citation | Wang, X; Zhang, W; Frye, S Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity US Patent US9649309 Publication Date 5/16/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein kinase receptor TYRO3 | |||
Name: | Tyrosine-protein kinase receptor TYRO3 | ||
Synonyms: | BYK | DTK | RSE | SKY | TIF | TYRO3 | TYRO3_HUMAN | Tyrosine-protein kinase SKY | ||
Type: | Protein | ||
Mol. Mass.: | 96894.13 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q06418 | ||
Residue: | 890 | ||
Sequence: |
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BDBM308189 | |||
n/a | |||
Name | BDBM308189 | ||
Synonyms: | US9649309, Compound UNC2547A | ||
Type | Small organic molecule | ||
Emp. Form. | C24H36N6O | ||
Mol. Mass. | 424.5822 | ||
SMILES | CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1ccc(CNCC2CC2)cn1 |r,wD:14.14,(-10.08,-3.85,;-8.75,-3.08,;-7.41,-3.85,;-6.08,-3.08,;-4.74,-3.85,;-3.41,-3.08,;-2.08,-3.85,;-.74,-3.08,;-.74,-1.54,;-2.08,-.77,;-2.08,.77,;-3.41,1.54,;-4.74,.77,;-6.08,1.54,;-6.08,3.08,;-7.41,3.85,;-4.74,3.85,;-3.41,3.08,;-3.41,-1.54,;.59,-.77,;1.92,-1.54,;3.26,-.77,;3.26,.77,;4.59,1.54,;5.92,.77,;7.26,1.54,;8.59,.77,;9.68,-.32,;10.08,1.17,;1.92,1.54,;.59,.77,)| | ||
Structure |