| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene C4 synthase |
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| Ligand | BDBM309974 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro hLTC4 Synthase Enzyme Assay |
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| IC50 | 149±n/a nM |
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| Citation |  Ronn, R; Lindh, CJ; Ringberg, E; Andersson, HB; Nilsson, P; Schaal, WR; Munck af Rosenschöld, M; Nikitidis, A; Nikitidis, G; Johannesson, P; Tyrchan, C Compounds and uses US Patent US9657001 Publication Date 5/23/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene C4 synthase |
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| Name: | Leukotriene C4 synthase |
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| Synonyms: | LTC4 synthase | LTC4S | LTC4S_HUMAN | Leukotriene-C(4) synthase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 16575.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_961179 |
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| Residue: | 150 |
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| Sequence: | MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
LAALGLLAHFLPAALRAALLGRLRTLLPWA
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| BDBM309974 |
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| n/a |
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| Name | BDBM309974 |
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| Synonyms: | US9657001, 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20ClF3N2O4 |
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| Mol. Mass. | 468.853 |
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| SMILES | COc1cc(cnc1C(=O)C1CC1C(O)=O)N(CC1(CC1)C(F)(F)F)c1ccc(Cl)cc1 |
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| Structure | 
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