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TargetLeukotriene C4 synthase
LigandBDBM223250
Substrate/Competitorn/a
Meas. Tech.In Vitro hLTC4 Synthase Enzyme Assay
IC50 66.0±n/a nM
Citation Ronn, RLindh, CJRingberg, EAndersson, HBNilsson, PSchaal, WRMunck af Rosenschöld, MNikitidis, ANikitidis, GJohannesson, PTyrchan, C Compounds and uses US Patent US9657001 Publication Date 5/23/2017
More Info.:Get all data from this article,  Assay Method
 
Leukotriene C4 synthase
Name:Leukotriene C4 synthase
Synonyms:LTC4 synthase | LTC4S | LTC4S_HUMAN | Leukotriene-C(4) synthase
Type:PROTEIN
Mol. Mass.:16575.59
Organism:Homo sapiens (Human)
Description:ChEMBL_961179
Residue:150
Sequence:
MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
LAALGLLAHFLPAALRAALLGRLRTLLPWA
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  Blast E-value cutoff:
BDBM223250
n/a
NameBDBM223250
Synonyms:2-(5-((Cyclopropylmethyl)(naphthalen-1-ylmethyl)amino)-3-methoxypicolinoyl)cyclopropanecarboxylic acid | US20160326143, 25 | US9657001, 25
TypeSmall Organic Molecule
Emp. Form.C26H26N2O4
Mol. Mass.430.4956
SMILESCOc1cc(cnc1C(=O)C1CC1C(O)=O)N(CC1CC1)Cc1cccc2ccccc12
Structure
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