| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Leukotriene C4 synthase |
|---|
| Ligand | BDBM223282 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro hLTC4 Synthase Enzyme Assay |
|---|
| IC50 | 50.0±n/a nM |
|---|
| Citation |  Ronn, R; Lindh, CJ; Ringberg, E; Andersson, HB; Nilsson, P; Schaal, WR; Munck af Rosenschöld, M; Nikitidis, A; Nikitidis, G; Johannesson, P; Tyrchan, C Compounds and uses US Patent US9657001 Publication Date 5/23/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Leukotriene C4 synthase |
|---|
| Name: | Leukotriene C4 synthase |
|---|
| Synonyms: | LTC4 synthase | LTC4S | LTC4S_HUMAN | Leukotriene-C(4) synthase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 16575.59 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_961179 |
|---|
| Residue: | 150 |
|---|
| Sequence: | MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYF
PLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVA
LAALGLLAHFLPAALRAALLGRLRTLLPWA
|
|
|
|---|
| BDBM223282 |
|---|
| n/a |
|---|
| Name | BDBM223282 |
|---|
| Synonyms: | 2-(5-((Cyclopropylmethyl)(naphthalen-1-yl)amino)-4-methoxypyrimidine-2-carbonyl)cyclopropanecarboxylic acid | US20160326143, 57 | US9657001, 57 |
|---|
| Type | Small Organic Molecule |
|---|
| Emp. Form. | C24H23N3O4 |
|---|
| Mol. Mass. | 417.4571 |
|---|
| SMILES | COc1nc(ncc1N(CC1CC1)c1cccc2ccccc12)C(=O)C1CC1C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
