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TargetHistone acetyltransferase KAT2B [719-832]
LigandBDBM311409
Substrate/Competitorn/a
Meas. Tech.PCAF AlphaLisa Binding Assay
IC50 87.0±n/a nM
Citation Albrecht, BKCote, ACrawford, TDuplessis, MGood, ACLeBlanc, YMagnuson, SNasveschuk, CGPastor, RRomero, AFTaylor, AM Therapeutic compounds and uses thereof US Patent US10155764 Publication Date 12/18/2018
More Info.:Get all data from this article,  Assay Method
 
Histone acetyltransferase KAT2B [719-832]
Name:Histone acetyltransferase KAT2B [719-832]
Synonyms:KAT2B | KAT2B_HUMAN | PCAF | PCAF (aa 719-832)
Type:Enzyme Catalytic Domain
Mol. Mass.:13623.13
Organism:Homo sapiens (Human)
Description:Q92831[719-832]
Residue:114
Sequence:
SKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLK
NRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM311409
n/a
NameBDBM311409
Synonyms:US10155764, Example 6
TypeSmall organic molecule
Emp. Form.C13H17FN4O
Mol. Mass.264.2987
SMILESCN(C)CCNc1nn(C)c(=O)c2c(F)cccc12
Structure
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