| Reaction Details |
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 | Report a problem with these data |
| Target | Calcitonin gene-related peptide 1 |
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| Ligand | BDBM311886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| Ki | 0.050±n/a nM |
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| Citation |  Christopher, JA; Congreve, MS; Bucknell, SJ; Deflorian, F; Pickworth, M; Mason, JS CGRP receptor antagonists US Patent US10166226 Publication Date 1/1/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcitonin gene-related peptide 1 |
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| Name: | Calcitonin gene-related peptide 1 |
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| Synonyms: | CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 13902.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06881 |
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| Residue: | 128 |
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| Sequence: | MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
RRRRDLQA
|
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|
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| BDBM311886 |
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| n/a |
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| Name | BDBM311886 |
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| Synonyms: | N-[(2R)-1-[4-(1H-imidazol-2-yl)-1,4'-bipiperidin-1'-yl]-3-(7-methyl-1H-indazol-5-yl)-1-oxopropan-2-yl]-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide | US10166226, Example 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H47N9O3 |
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| Mol. Mass. | 689.849 |
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| SMILES | Cc1cc(C[C@@H](NC(=O)N2CCC(CC2)c2cc3ccccc3[nH]c2=O)C(=O)N2CCC(CC2)N2CCC(CC2)c2ncc[nH]2)cc2cn[nH]c12 |r| |
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| Structure | 
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