| Reaction Details |
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 | Report a problem with these data |
| Target | Calcitonin gene-related peptide 1 |
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| Ligand | BDBM312052 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| Ki | 0.100±n/a nM |
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| Citation |  Christopher, JA; Congreve, MS; Bucknell, SJ; Deflorian, F; Pickworth, M; Mason, JS CGRP receptor antagonists US Patent US10166226 Publication Date 1/1/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcitonin gene-related peptide 1 |
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| Name: | Calcitonin gene-related peptide 1 |
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| Synonyms: | CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 13902.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06881 |
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| Residue: | 128 |
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| Sequence: | MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
RRRRDLQA
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|
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| BDBM312052 |
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| n/a |
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| Name | BDBM312052 |
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| Synonyms: | N-{(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(5-methyl-4H-1,2,4-triazol-3-yl)-1,4'-bipiperidin-1'-yl]-1-oxopropan-2-yl}-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide | US10166226, Example 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H48N10O3 |
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| Mol. Mass. | 704.8636 |
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| SMILES | Cc1nnc([nH]1)C1CCN(CC1)C1CCN(CC1)C(=O)[C@@H](Cc1cc(C)c2[nH]ncc2c1)NC(=O)N1CCC(CC1)c1cc2ccccc2[nH]c1=O |r| |
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| Structure | 
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