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TargetAmine oxidase [flavin-containing] A
LigandBDBM179976
Substrate/Competitorn/a
Meas. Tech.Monoamine Oxidase Assays
pH7.5±n/a
Ki 50±n/a nM
Commentsextracted
Citation Fyfe MCOrtega Muñoz ACastro-Palomino Laria JMartinell Pedemonte MEstiarte-Martinez MValls Vidal N Cyclopropylamine derivatives useful as LSD1 inhibitors US Patent  US9676701 Publication Date 6/13/2017
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] A
Name:Amine oxidase [flavin-containing] A
Synonyms:Amine oxidase (flavin-containing) A | MAO-A | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:Protein
Mol. Mass.:59689.53
Organism:Homo sapiens (Human)
Description:P21397
Residue:527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
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  Blast E-value cutoff:
BDBM179976
n/a
NameBDBM179976
Synonyms:US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)thiazol-2-yl)phenol hydrochloride
TypeSmall organic molecule
Emp. Form.C12H12N2OS
Mol. Mass.232.301
SMILESN[C@H]1C[C@@H]1c1cnc(s1)-c1cccc(O)c1 |r|
Structure
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