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TargetIntermediate conductance calcium-activated potassium channel protein 4
LigandBDBM314198
Substrate/Competitorn/a
Meas. Tech.Electrophysiology Assay
IC50 58.0±n/a nM
Citation Green LWang H Oxazolidinone and imidazolidinone compounds US Patent  US9611232 Publication Date 4/4/2017
More Info.:Get all data from this article,  Assay Method
 
Intermediate conductance calcium-activated potassium channel protein 4
Name:Intermediate conductance calcium-activated potassium channel protein 4
Synonyms:IK1 | IKCa1 | KCa4 | Putative Gardos channel | SK4
Type:PROTEIN
Mol. Mass.:47723.22
Organism:Homo sapiens (Human)
Description:ChEMBL_1361891
Residue:427
Sequence:
MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL
VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA
PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR
SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT
LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN
FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK
LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP
EPSQQSK
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  Blast E-value cutoff:
BDBM314198
n/a
NameBDBM314198
Synonyms:(S)-2-(5,5-bis(4-fluorophenyl)-2-oxo-4-phenyloxazolidin-3-yl)acetamide | US9611232, Example 1
TypeSmall organic molecule
Emp. Form.C23H18F2N2O3
Mol. Mass.408.3974
SMILESNC(=O)CN1[C@@H](c2ccccc2)C(OC1=O)(c1ccc(F)cc1)c1ccc(F)cc1 |r|
Structure
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