| Reaction Details |
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 | Report a problem with these data |
| Target | Intermediate conductance calcium-activated potassium channel protein 4 |
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| Ligand | BDBM314215 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Electrophysiology Assay |
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| IC50 | 45.0±n/a nM |
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| Citation |  Green, L; Wang, H Oxazolidinone and imidazolidinone compounds US Patent US9611232 Publication Date 4/4/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Intermediate conductance calcium-activated potassium channel protein 4 |
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| Name: | Intermediate conductance calcium-activated potassium channel protein 4 |
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| Synonyms: | IK1 | IKCA1 | KCA4 | KCNN4 | KCNN4_HUMAN | Putative Gardos channel | SK4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47723.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1361891 |
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| Residue: | 427 |
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| Sequence: | MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL
VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA
PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR
SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT
LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN
FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK
LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP
EPSQQSK
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| BDBM314215 |
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| n/a |
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| Name | BDBM314215 |
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| Synonyms: | US9611232, Example 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H17F3N2O3 |
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| Mol. Mass. | 426.3879 |
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| SMILES | NC(=O)CN1[C@@H](c2ccc(F)cc2)C(OC1=O)(c1ccc(F)cc1)c1ccc(F)cc1 |r| |
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| Structure | 
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