| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform alpha |
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| Ligand | BDBM10842 |
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| Substrate/Competitor | Casein |
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| Meas. Tech. | Kinase Inhibition Assay |
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| Temperature | 303.15±n/a K |
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| IC50 | 400±n/a nM |
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| Comments | extracted |
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| Citation |  Gompel, M; Leost, M; De Kier Joffe, EB; Puricelli, L; Franco, LH; Palermo, J; Meijer, L Meridianins, a new family of protein kinase inhibitors isolated from the ascidian Aplidium meridianum. Bioorg Med Chem Lett14:1703-7 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Casein kinase I isoform alpha |
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| Name: | Casein kinase I isoform alpha |
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| Synonyms: | CK1 | CKI-alpha | Casein Kinase I | Csnk1a1 | KC1A_RAT |
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| Type: | Enzyme |
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| Mol. Mass.: | 37514.97 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 325 |
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| Sequence: | MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
SKLYKILQGGVGIPHIRWYGQGKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
LKQKAAQQAASSSGQGQQAQTPTGF
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| BDBM10842 |
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| Casein |
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| Name: | Casein |
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| Synonyms: | n/a |
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| Type: | Other Protein Type |
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| Mol. Mass.: | 20807.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 177 |
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| Sequence: | MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ
TDEIKDTRNESTQNCVVAESEKMESSISSSSEEQFCRLNEYNQLQLQAAHAQEQIRRMNE
NSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNNVMLQW
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