| Reaction Details |
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 | Report a problem with these data |
| Target | CARBONIC ANHYDRASE |
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| Ligand | BDBM10889 |
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| Substrate/Competitor | BDBM10856 |
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| Meas. Tech. | CA Inhibition Assay |
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| Ki | 204±n/a nM |
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| Citation |  Nishimori, I; Minakuchi, T; Morimoto, K; Sano, S; Onishi, S; Takeuchi, H; Vullo, D; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs. J Med Chem49:2117-26 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| CARBONIC ANHYDRASE |
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| Name: | CARBONIC ANHYDRASE |
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| Synonyms: | Carbonic Anhydrase (hpCA) | hpCA |
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| Type: | Enzyme |
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| Mol. Mass.: | 28277.52 |
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| Organism: | Helicobacter pylori J99 |
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| Description: | Q9ZK30 |
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| Residue: | 247 |
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| Sequence: | MKKTFLIALALTASLIGAENTKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYY
HTQDKADLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLIN
NKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEGIQKKQNLKEVALDAFLPKS
INYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVII
KSSAETR
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| BDBM10889 |
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| BDBM10856 |
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| Name | BDBM10889 |
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| Synonyms: | 2-methoxy-N-[(1-methylpyrrolidin-2-yl)methyl]-5-sulfamoylbenzamide | Sulmepride | Sulpiride (SLP) |
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| Type | Small organic molecule |
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| Emp. Form. | C14H21N3O4S |
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| Mol. Mass. | 327.399 |
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| SMILES | COc1ccc(cc1C(=O)NCC1CCCN1C)S(N)(=O)=O |
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| Structure | 
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