| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform alpha |
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| Ligand | BDBM7533 |
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| Substrate/Competitor | Casein |
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| Meas. Tech. | Kinase Inhibition Assay |
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| pH | 7.2±n/a |
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| Temperature | 303.15±n/a K |
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| IC50 | 100000±n/a nM |
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| Citation |  Tang, L; Li, MH; Cao, P; Wang, F; Chang, WR; Bach, S; Reinhardt, J; Ferandin, Y; Galons, H; Wan, Y; Gray, N; Meijer, L; Jiang, T; Liang, DC Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives. J Biol Chem280:31220-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Casein kinase I isoform alpha |
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| Name: | Casein kinase I isoform alpha |
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| Synonyms: | CK1 | CKI-alpha | Casein Kinase I | Csnk1a1 | KC1A_RAT |
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| Type: | Enzyme |
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| Mol. Mass.: | 37514.97 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 325 |
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| Sequence: | MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
SKLYKILQGGVGIPHIRWYGQGKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
LKQKAAQQAASSSGQGQQAQTPTGF
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| BDBM7533 |
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| Casein |
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| Name: | Casein |
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| Synonyms: | n/a |
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| Type: | Other Protein Type |
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| Mol. Mass.: | 20807.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 177 |
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| Sequence: | MRLLILTCLVAVALARPKLPLRYPERLQNPSESSEPIPLESREEYMNGMNRQRNILREKQ
TDEIKDTRNESTQNCVVAESEKMESSISSSSEEQFCRLNEYNQLQLQAAHAQEQIRRMNE
NSHVQVPFQQLNQLAAYPYAVWYYPQIMQYVPFPPFSDISNPTAHENYEKNNVMLQW
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