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Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Solute carrier family 22 member 12 | ||
| Ligand | BDBM318941 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | HEK-URAT1 assay | ||
| IC50 | 2060±n/a nM | ||
| Citation |  Endo, T; Kobayashi, K; Tanaka, H; Saito, D; Hirano, M; Endou, H; Anzai, N URAT1 inhibitor US Patent US10173990 Publication Date 1/8/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Solute carrier family 22 member 12 | |||
| Name: | Solute carrier family 22 member 12 | ||
| Synonyms: | OATL4 | Organic anion transporter 4-like protein | RST | Renal-specific transporter | S22AC_HUMAN | SLC22A12 | Solute carrier family 22 member 12 | Solute carrier family 22 member 12 (URAT1) | URAT1 | Urate anion exchanger 1 | Urate anion exchanger 1 (URAT1) | Uric Acid Transporter 1 (URAT1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 59638.65 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q96S37 | ||
| Residue: | 553 | ||
| Sequence: |
| ||
| BDBM318941 | |||
| n/a | |||
| Name | BDBM318941 | ||
| Synonyms: | 2-[(4′-Cyano-(1,1′-binaphthalene)-2-yl]oxy]-2-methylpropanoic acid | US10173990, Example 2 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H19NO3 | ||
| Mol. Mass. | 381.4233 | ||
| SMILES | CC(C)(Oc1ccc2ccccc2c1-c1ccc(C#N)c2ccccc12)C(O)=O |(-3.75,-2.29,;-4.52,-.95,;-5.29,.38,;-3.19,-.18,;-1.85,-.95,;-1.85,-2.49,;-.52,-3.26,;.81,-2.49,;2.15,-3.26,;3.48,-2.49,;3.48,-.95,;2.15,-.18,;.81,-.95,;-.52,-.18,;-.52,1.36,;-1.85,2.13,;-1.85,3.67,;-.52,4.44,;-.52,5.98,;-.52,7.52,;.81,3.67,;2.15,4.44,;3.48,3.67,;3.48,2.13,;2.15,1.36,;.81,2.13,;-5.85,-1.72,;-5.85,-3.26,;-7.19,-.95,)| | ||
| Structure | 
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