Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCapsid protein
LigandBDBM324422
Substrate/Competitorn/a
Meas. Tech.BDNA-assay
EC50<100±n/a nM
Citation Hartman, GDKuduk, S Derivatives and methods of treating hepatitis B infections US Patent US10189835 Publication Date 1/29/2019
More Info.:Get all data from this article,  Assay Method
 
Capsid protein
Name:Capsid protein
Synonyms:C | CAPSD_HBVCJ | Core antigen | Core protein | HBcAg | p21.5
Type:Enzyme Catalytic Domain
Mol. Mass.:21105.01
Organism:Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-) (HBV-C)
Description:n/a
Residue:183
Sequence:
MDIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAIL
CWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLV
SFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRE
SQC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM324422
n/a
NameBDBM324422
Synonyms:US10189835, Compound 698
TypeSmall organic molecule
Emp. Form.C17H17ClFN5O3
Mol. Mass.393.8
SMILESFC1CON(C1)C(=O)c1n[nH]c2CCN(Cc12)C(=O)Nc1cccc(Cl)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: