| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M3 |
|---|
| Ligand | BDBM193834 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Receptor Selection and Amplification Assays |
|---|
| EC50 | 79±n/a nM |
|---|
| Citation |  Burstein, ES; Eskildsen, J; Olsson, R Muscarinic agonists US Patent US9670209 Publication Date 6/6/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M3 |
|---|
| Name: | Muscarinic acetylcholine receptor M3 |
|---|
| Synonyms: | ACM3_HUMAN | CHRM3 | Cholinergic, muscarinic M3 | Muscarinic Receptors M3 | Muscarinic receptor M3 | RecName: Full=Muscarinic acetylcholine receptor M3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 66151.03 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P20309 |
|---|
| Residue: | 590 |
|---|
| Sequence: | MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPL
GGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVI
SMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR
TTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAF
YMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSM
KRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSE
TRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSF
PKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKR
MSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVN
PVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL
|
|
|
|---|
| BDBM193834 |
|---|
| n/a |
|---|
| Name | BDBM193834 |
|---|
| Synonyms: | US9670209, Comparative compound 2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H21NO3 |
|---|
| Mol. Mass. | 227.3 |
|---|
| SMILES | CC(C)(C)OC(=O)N1C2CC[C@H]1C[C@@H](O)C2 |r,$_AV:13;11;14;15;4;;7;1;2;9;10;3;5;8;12;6$,THB:14:13:7:9.10| |
|---|
| Structure | 
|
|---|
Search and Browse
