| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM11930 |
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| Substrate/Competitor | BDBM11402 |
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| Meas. Tech. | In Vitro Binding for Human Carbonic Anhydrase II |
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| pH | 7.4±n/a |
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| Temperature | 310.15±n/a K |
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| Kd | 0.49±.11 nM |
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| Citation |  Boriack-Sjodin, PA; Zeitlin, S; Chen, HH; Crenshaw, L; Gross, S; Dantanarayana, A; Delgado, P; May, JA; Dean, T; Christianson, DW Structural analysis of inhibitor binding to human carbonic anhydrase II. Protein Sci7:2483-9 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM11930 |
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| BDBM11402 |
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| Name | BDBM11930 |
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| Synonyms: | 2-N-[(4-methoxyphenyl)methyl]thiophene-2,5-disulfonamide | AL5927 | N-[(4-METHOXYPHENYL)METHYL]2,5-THIOPHENEDESULFONAMIDE |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14N2O5S3 |
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| Mol. Mass. | 362.445 |
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| SMILES | COc1ccc(CNS(=O)(=O)c2ccc(s2)S(N)(=O)=O)cc1 |
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| Structure | 
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