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TargetCarbonic anhydrase 2
LigandBDBM11934
Substrate/CompetitorBDBM11402
Meas. Tech.In Vitro Binding for Human Carbonic Anhydrase II
pH7.4±n/a
Temperature310.15±n/a K
Kd 0.32±.05 nM
Citation Boriack-Sjodin PAZeitlin SChen HHCrenshaw LGross SDantanarayana ADelgado PMay JADean TChristianson DW Structural analysis of inhibitor binding to human carbonic anhydrase II. Protein Sci 7:2483-9 (1998) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Carbonic anhydrase 2
Name:Carbonic anhydrases; II & IX
Synonyms:CA-II | CA2 | CAC | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:Enzyme
Mol. Mass.:29250.71
Organism:Homo sapiens (Human)
Description:P00918
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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BDBM11934
BDBM11402
NameBDBM11934
Synonyms:(4R)-4-(ethylamino)-2-(2-methoxyethyl)-1,1-dioxo-2H,3H,4H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide | (R)-4-ETHYLAMINO-3,4-DIHYDRO-2-(2-METHOYLETHYL)-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE | AL4623
TypeSmall organic molecule
Emp. Form.C11H19N3O5S3
Mol. Mass.369.481
SMILESCCN[C@H]1CN(CCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O |r|
Structure
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