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TargetCarbonic anhydrase 2
LigandBDBM11938
Substrate/CompetitorBDBM11402
Meas. Tech.In Vitro Binding for Human Carbonic Anhydrase II
pH7.4±n/a
Temperature310.15±n/a K
Kd 0.13±.03 nM
Commentssingle determination.
Citation Boriack-Sjodin PAZeitlin SChen HHCrenshaw LGross SDantanarayana ADelgado PMay JADean TChristianson DW Structural analysis of inhibitor binding to human carbonic anhydrase II. Protein Sci 7:2483-9 (1998) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Carbonic anhydrase 2
Name:Carbonic anhydrases; II & IX
Synonyms:CA-II | CA2 | CAC | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:Enzyme
Mol. Mass.:29250.71
Organism:Homo sapiens (Human)
Description:P00918
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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BDBM11938
BDBM11402
NameBDBM11938
Synonyms:2-(3-METHOXYPHENYL)-2H-THIENO-[3,2-E]-1,2-THIAZINE-6-SULFINAMIDE-1,1-DIOXIDE | 2-(3-methoxyphenyl)-1,1-dioxo-2H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide | AL6528
TypeSmall organic molecule
Emp. Form.C13H12N2O5S3
Mol. Mass.372.44
SMILESCOc1cccc(c1)N1C=Cc2cc(sc2S1(=O)=O)S(N)(=O)=O |c:10|
Structure
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