| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 [F130V] |
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| Ligand | BDBM12015 |
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| Substrate/Competitor | BDBM11402 |
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| Meas. Tech. | In vitro binding of inhibitor to hCA-II |
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| pH | 7.4±n/a |
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| Temperature | 310.15±n/a K |
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| Kd | 3.3±n/a nM |
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| Citation |  Kim, CY; Chandra, PP; Jain, A; Christianson, DW Fluoroaromatic-fluoroaromatic interactions between inhibitors bound in the crystal lattice of human carbonic anhydrase II. J Am Chem Soc123:9620-7 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Carbonic anhydrase 2 [F130V] |
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| Name: | Carbonic anhydrase 2 [F130V] |
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| Synonyms: | CA-II | CA2 | CAH2_HUMAN | Carbonate dehydratase II | Carbonic Anhydrase II Mutant (F130V) | Carbonic anhydrase C |
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| Type: | Enzyme |
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| Mol. Mass.: | 29202.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918[F130V] |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDVGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM12015 |
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| BDBM11402 |
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| Name | BDBM12015 |
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| Synonyms: | 4-(AMINOSULFONYL)-N-[(4-FLUOROPHENYL)METHYL]-BENZAMIDE | 4-fluoro-SBB | N-[(4-fluorophenyl)methyl]-4-sulfamoylbenzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13FN2O3S |
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| Mol. Mass. | 308.328 |
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| SMILES | NS(=O)(=O)c1ccc(cc1)C(=O)NCc1ccc(F)cc1 |
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| Structure | 
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