Reaction Details |
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Target | Sigma intracellular receptor 2 |
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Ligand | BDBM50353847 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Receptor Assay |
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Ki | 0.210±0.020 nM |
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Citation | McCurdy, CR; Mesangeau, C; Chin, FT; James, ML; Shen, B; Gambhir, S; Biswal, S; Behera, D Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders US Patent US9724435 Publication Date 8/8/2017 |
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More Info.: | Get all data from this article, Assay Method |
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Sigma intracellular receptor 2 |
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Name: | Sigma intracellular receptor 2 |
Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
Type: | Protein |
Mol. Mass.: | 20953.88 |
Organism: | Rattus norvegicus (Rat) |
Description: | Q5U3Y7 |
Residue: | 176 |
Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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BDBM50353847 |
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n/a |
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Name | BDBM50353847 |
Synonyms: | CHEMBL1831157 | US9604926, Compound CM-360 | US9724435, Compound CM-360 |
Type | Small organic molecule |
Emp. Form. | C23H28N2O2 |
Mol. Mass. | 364.4806 |
SMILES | COc1cc2CCN(CCCCn3ccc4ccccc34)Cc2cc1OC |
Structure |
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