| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Ligand | BDBM330386 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cyp11 Assay |
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| IC50 | 1800±n/a nM |
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| Citation |  Blass, BE; Abou-Gharbia, MA; Childers, WE; Iyer, P; Boruwa, J Cytochrome P450 inhibitors and their method of use US Patent US9725436 Publication Date 8/8/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Name: | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Synonyms: | CP11A_BOVIN | CYP11A1 | CYPXIA1 | Cholesterol desmolase | Cholesterol side-chain cleavage enzyme, mitochondrial | Cytochrome P450 11A1 | Cytochrome P450 11A1 (CYP11A1) | P450(scc) |
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| Type: | Protein |
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| Mol. Mass.: | 60346.75 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | P00189 |
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| Residue: | 520 |
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| Sequence: | MLARGLPLRSALVKACPPILSTVGEGWGHHRVGTGEGAGISTKTPRPYSEIPSPGDNGWL
NLYHFWREKGSQRIHFRHIENFQKYGPIYREKLGNLESVYIIHPEDVAHLFKFEGSYPER
YDIPPWLAYHRYYQKPIGVLFKKSGTWKKDRVVLNTEVMAPEAIKNFIPLLNPVSQDFVS
LLHKRIKQQGSGKFVGDIKEDLFHFAFESITNVMFGERLGMLEETVNPEAQKFIDAVYKM
FHTSVPLLNVPPELYRLFRTKTWRDHVAAWDTIFNKAEKYTEIFYQDLRRKTEFRNYPGI
LYCLLKSEKMLLEDVKANITEMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLNARR
QAEGDISKMLQMVPLLKASIKETLRLHPISVTLQRYPESDLVLQDYLIPAKTLVQVAIYA
MGRDPAFFSSPDKFDPTRWLSKDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILE
NFKVEMQHIGDVDTIFNLILTPDKPIFLVFRPFNQDPPQA
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| BDBM330386 |
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| n/a |
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| Name | BDBM330386 |
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| Synonyms: | US9725436, Entry 6 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25FN4O |
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| Mol. Mass. | 428.5013 |
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| SMILES | Fc1cc(\C=C\c2ccc(cc2)N2CCN(CC2)C2=NCCO2)cc(c1)-c1ccncc1 |t:20| |
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| Structure | 
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