| Reaction Details |
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 | Report a problem with these data |
| Target | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Ligand | BDBM330389 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cyp11 Assay |
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| IC50 | 58.0±n/a nM |
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| Citation |  Blass, BE; Abou-Gharbia, MA; Childers, WE; Iyer, P; Boruwa, J Cytochrome P450 inhibitors and their method of use US Patent US9725436 Publication Date 8/8/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Name: | Cholesterol side-chain cleavage enzyme, mitochondrial |
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| Synonyms: | CP11A_BOVIN | CYP11A1 | CYPXIA1 | Cholesterol desmolase | Cholesterol side-chain cleavage enzyme, mitochondrial | Cytochrome P450 11A1 | Cytochrome P450 11A1 (CYP11A1) | P450(scc) |
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| Type: | Protein |
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| Mol. Mass.: | 60346.75 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | P00189 |
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| Residue: | 520 |
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| Sequence: | MLARGLPLRSALVKACPPILSTVGEGWGHHRVGTGEGAGISTKTPRPYSEIPSPGDNGWL
NLYHFWREKGSQRIHFRHIENFQKYGPIYREKLGNLESVYIIHPEDVAHLFKFEGSYPER
YDIPPWLAYHRYYQKPIGVLFKKSGTWKKDRVVLNTEVMAPEAIKNFIPLLNPVSQDFVS
LLHKRIKQQGSGKFVGDIKEDLFHFAFESITNVMFGERLGMLEETVNPEAQKFIDAVYKM
FHTSVPLLNVPPELYRLFRTKTWRDHVAAWDTIFNKAEKYTEIFYQDLRRKTEFRNYPGI
LYCLLKSEKMLLEDVKANITEMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLNARR
QAEGDISKMLQMVPLLKASIKETLRLHPISVTLQRYPESDLVLQDYLIPAKTLVQVAIYA
MGRDPAFFSSPDKFDPTRWLSKDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILE
NFKVEMQHIGDVDTIFNLILTPDKPIFLVFRPFNQDPPQA
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| BDBM330389 |
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| n/a |
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| Name | BDBM330389 |
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| Synonyms: | US9725436, Entry 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28ClN3O2S |
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| Mol. Mass. | 482.037 |
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| SMILES | CC(C)S(=O)(=O)N1CCN(CC1)c1ccc(\C=C\c2cc(Cl)cc(c2)-c2ccncc2)cc1 |
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| Structure | 
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