| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor 2 |
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| Ligand | BDBM330452 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Receptor Binding Inhibition Assay |
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| Ki | 1.60±n/a nM |
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| Citation |  Hata, K; Masuda, M; Nakai, H; Taniyama, D; Tobinaga, H; Hato, Y; Fujiu, M Heterocyclic derivative having PGD2 receptor antagonist activity US Patent US9725442 Publication Date 8/8/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor 2 |
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| Name: | Prostaglandin D2 receptor 2 |
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| Synonyms: | CD_antigen=CD294 | CRTH2 | Chemoattractant Receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) | Chemoattractant receptor-homologous molecule expressed on Th2 cells | Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | DL1R | G protein-coupled receptor 44 | G-protein coupled receptor 44 | GPR44 | PD2R2_HUMAN | PTGDR2 | Prostaglandin D2 | Prostaglandin D2 receptor 2 | Prostaglandin D2 receptor 2 (PGD2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 43295.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y5Y4 |
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| Residue: | 395 |
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| Sequence: | MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCR
MRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGF
LLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRI
MCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRR
PGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVAN
PVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRP
EEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
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| BDBM330452 |
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| n/a |
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| Name | BDBM330452 |
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| Synonyms: | US9725442, Compound I-117 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22FN3O4S |
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| Mol. Mass. | 431.48 |
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| SMILES | C[C@@H]1CN(C[C@@H]1n1nc(CC(O)=O)c2ccc(F)cc12)S(=O)(=O)c1ccc(C)cc1 |r| |
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| Structure | 
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