| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM65513 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | D2R Binding Assay |
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| Ki | >250000±0 nM |
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| Citation |  Jones, CL; Njomen, E; Sjögren, B; Dexheimer, TS; Tepe, JJ Small Molecule Enhancement of 20S Proteasome Activity Targets Intrinsically Disordered Proteins. ACS Chem Biol12:2240-2247 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM65513 |
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| n/a |
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| Name | BDBM65513 |
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| Synonyms: | CPZ analog, 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14ClNO2S |
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| Mol. Mass. | 367.849 |
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| SMILES | OC(=O)c1ccc(CN2c3ccccc3Sc3ccc(Cl)cc23)cc1 |
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| Structure | 
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