| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM333246 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Assay for Binding Affinity for Adenosine Receptor A3 |
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| Ki | <10±n/a nM |
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| Citation |  Lee, J; Kim, S; Kim, D; Ahn, K; Lee, G; Kim, D; Hwang, H Compounds antagonizing A3 adenosine receptor, method for preparing them, and medical-use thereof US Patent US10196396 Publication Date 2/5/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM333246 |
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| n/a |
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| Name | BDBM333246 |
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| Synonyms: | (2S,3R,4S)-2-(8-((4-methylpiperazin-1-yl)amino)-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)tetrahydrothiophene-3,4-diol | US10196396, Compound 41 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H21N7O2S |
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| Mol. Mass. | 351.427 |
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| SMILES | CN1CCN(CC1)Nc1nccn2c(nnc12)[C@@H]1SC[C@@H](O)[C@H]1O |
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| Structure | 
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