| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP3 subtype |
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| Ligand | BDBM335701 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand SPA Binding Assay |
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| Ki | 8.90±n/a nM |
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| Citation |  Bahnck, K; Canterbury, D; Edmonds, DJ; Futatsugi, K; Lee, EC; Menhaji-Klotz, E; Polivkova, J; Stanton, RV Antagonists of prostaglandin EP3 receptor US Patent US9738626 Publication Date 8/22/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP3 subtype |
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| Name: | Prostaglandin E2 receptor EP3 subtype |
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| Synonyms: | PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 43335.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43115 |
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| Residue: | 390 |
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| Sequence: | MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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| BDBM335701 |
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| n/a |
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| Name | BDBM335701 |
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| Synonyms: | (R)-6-(5-Chloroquinolin-7-yl)-3-(3-methyl-2-oxopiperidin-3-yl)pyridin-2(1H)-one | US9738626, 4 (free base and TFA salt) |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18ClN3O2 |
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| Mol. Mass. | 367.829 |
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| SMILES | C[C@@]1(CCCNC1=O)c1ccc([nH]c1=O)-c1cc(Cl)c2cccnc2c1 |
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| Structure | 
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