| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kallikrein-7 |
|---|
| Ligand | BDBM336134 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| IC50 | 130±n/a nM |
|---|
| Citation |  Linschoten, M Kallikrein 7 inhibitors US Patent US9744148 Publication Date 8/29/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kallikrein-7 |
|---|
| Name: | Kallikrein-7 |
|---|
| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 27535.05 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1469257 |
|---|
| Residue: | 253 |
|---|
| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
|
|
|
|---|
| BDBM336134 |
|---|
| n/a |
|---|
| Name | BDBM336134 |
|---|
| Synonyms: | US9744148, 7 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18N2O5 |
|---|
| Mol. Mass. | 318.3245 |
|---|
| SMILES | COc1ccc(CC(=O)OC(C)C(=O)Nc2cc(C)on2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
