| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Calcium-dependent protein kinase 1 |
|---|
| Ligand | BDBM340899 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Biological Assay |
|---|
| IC50 | 7.30±n/a nM |
|---|
| Citation |  Van Voorhis, WC; Hol, WG; Larson, ET; Maly, DJ; Merritt, E; Ojo, KK Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases US Patent US9765037 Publication Date 9/19/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Calcium-dependent protein kinase 1 |
|---|
| Name: | Calcium-dependent protein kinase 1 |
|---|
| Synonyms: | Calcium-dependent protein kinase 1 (CDPK1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 76617.33 |
|---|
| Organism: | Cryptosporidium parvum |
|---|
| Description: | Q6S4W0 |
|---|
| Residue: | 677 |
|---|
| Sequence: | MLNIEQNADECAKRVGANMVPVLHNVTEECNIKAEEKEIVPEVEEAKSESNNCLDSDDYL
EGHIYAAMCTKCAGELQQKLNPTEPYRDPKKVSGKEQISRGLIIESKSFVDANKNIKFSK
RSDKNEYAGLCSSPEVTTPNGERETSTDSNIKNTESTKVSHGIFDRTCLIQEHALVNRNI
NDFYELNLGNLGRGSYGSVVKAIDKQSGAQRAVKIILKPKLENINRLKREILIMKRLDHP
NIIKLFEVFEDTNYLYFVMEICTGGELFDRIIKRGHFSERYAAVIMRQVFSAIAYCHSNE
FMHRDLKPENLLFSDSSPNSLLKVIDWGFAAKCPKTHKFTSVVGTPYYVAPEVLYGSYSK
LCDLWSAGVILYILLCGYPPFHGKDNVEILRKVKIGQYSLEHNSWKYVSDSAKDLIKRLL
MTDPNKRISAQDALNHPWIKSQISSPNTADATYFTNDVCNSLLARFRDFQRQSKLKKLAL
TCVAYHLNDADIGALQKLFSTLDRNGDGVLTINEIRSALHKIQNVSQLGDDIDNLLMELD
TDGNGRIDYTEFIAASIDHKLYEQESLCKAAFKVFDLDMDGRISPQELSRVLNITFLQEA
FEQSTIDSLLKEVDINQDGYIDFNEFMKMMMGDKHEQKLETKVQKIEDEGSGNKKLSKGG
IISDIFGATSIFKKLNN
|
|
|
|---|
| BDBM340899 |
|---|
| n/a |
|---|
| Name | BDBM340899 |
|---|
| Synonyms: | 1-isopropyl-3-(4-methyl-1H-indol-2-yl)-1H- pyrazolo[3,4-d]pyrimidin-4-amine | US10544104, Compound 25 | US11247972, Compound 25 | US9765037, Compound 25 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18N6 |
|---|
| Mol. Mass. | 306.365 |
|---|
| SMILES | CC(C)n1nc(-c2cc3c(C)cccc3[nH]2)c2c(N)ncnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
