| Reaction Details |
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 | Report a problem with these data |
| Target | Large neutral amino acids transporter small subunit 1 |
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| Ligand | BDBM340671 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibitory Activity Assay |
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| IC50 | 69000±n/a nM |
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| Citation |  Kanai, Y; Nagamori, S; Kitaura, Y; Neya, M; Matsushita, N Phenoxyalkylamine compound US Patent US9771316 Publication Date 9/26/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Large neutral amino acids transporter small subunit 1 |
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| Name: | Large neutral amino acids transporter small subunit 1 |
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| Synonyms: | 4F2 LC | 4F2 light chain | 4F2LC | CD98 light chain | CD98LC | CD98LC | Integral membrane protein E16 | L-type amino acid transporter 1 | LAT1 | LAT1_HUMAN | Large neutral amino acids transporter small subunit 1 | MPE16 | SLC7A5 | Solute carrier family 7 member 5 | hLAT1 | y+ system cationic amino acid transporter |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55013.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_100160 |
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| Residue: | 507 |
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| Sequence: | MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIV
GTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYM
LEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVL
LLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDV
GNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTL
STEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLP
SILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVINFFSFFNWLCVALAIIGMIWLRH
RKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGFTIILSGLPVYFFGVWWKN
KPKWLLQGIFSTTVLCQKLMQVVPQET
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| BDBM340671 |
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| n/a |
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| Name | BDBM340671 |
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| Synonyms: | US9771316, Example 69 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19F4NO |
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| Mol. Mass. | 341.3432 |
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| SMILES | NCCCC[C@H](Oc1ccc(c(F)c1)C(F)(F)F)c1ccccc1 |r| |
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| Structure | 
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