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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium channel protein type 9 subunit alpha | ||
| Ligand | BDBM145318 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Electrophysiological Assay (In Vitro Assay) | ||
| IC50 | 7.30±n/a nM | ||
| Citation |  Chowdhury, S; Dehnhardt, CM; Focken, T; Grimwood, ME; Hemeon, IW; Jia, Q; Ortwine, DF; Safina, B; Sun, S; Sutherlin, DP; Zenova, AY N-substituted benzamides and methods of use thereof US Patent US9771376 Publication Date 9/26/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium channel protein type 9 subunit alpha | |||
| Name: | Sodium channel protein type 9 subunit alpha | ||
| Synonyms: | NENA | Neuroendocrine sodium channel | Peripheral sodium channel 1 | SCN9A | SCN9A_HUMAN | Sodium channel protein type IX alpha subunit | Voltage-gated sodium channel subunit Nav1.7 | Voltage-gated sodium channel subunit alpha Nav1.7 | hNE-Na | ||
| Type: | Protein | ||
| Mol. Mass.: | 226375.97 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15858 | ||
| Residue: | 1988 | ||
| Sequence: |
| ||
| BDBM145318 | |||
| n/a | |||
| Name | BDBM145318 | ||
| Synonyms: | US8952169, 97 | US9771376, Example 97 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H26ClFN2O4S | ||
| Mol. Mass. | 444.948 | ||
| SMILES | CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCC2C3CC4CC(C3)CC2C4)cc1F |TLB:15:16:18:20.21.22,THB:16:24:20:18.17.22,16:17:20:24.23.25,23:24:18:20.21.22,23:21:18:24.16.25,(8.42,2.5,;7.08,1.73,;7.08,.19,;5.75,2.5,;4.98,3.84,;6.52,3.84,;4.42,1.73,;3.08,2.5,;3.08,4.04,;1.75,1.73,;1.75,.19,;.41,-.58,;.41,-2.12,;-.92,.19,;-2.25,-.58,;-3.59,.19,;-4.92,-.58,;-6.25,.19,;-7.58,-.58,;-7.58,-2.12,;-8.42,-4.02,;-7.02,-3.37,;-7,-.97,;-5.82,-4.04,;-4.92,-2.12,;-6.25,-2.89,;-.92,1.73,;.41,2.5,;.41,4.04,)| | ||
| Structure | 
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