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TargetSigma intracellular receptor 2
LigandBDBM349507
Substrate/Competitorn/a
Meas. Tech.Competitive Radioligand Binding Assay 2
Ki 23.0±n/a nM
Citation Rishton, GMCatalano, SMLook, GC Isoindoline compositions and methods for treating neurodegenerative disease US Patent US10207991 Publication Date 2/19/2019
More Info.:Get all data from this article,  Assay Method
 
Sigma intracellular receptor 2
Name:Sigma intracellular receptor 2
Synonyms:MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:Protein
Mol. Mass.:20857.20
Organism:Homo sapiens (Human)
Description:Q5BJF2
Residue:176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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  Blast E-value cutoff:
BDBM349507
n/a
NameBDBM349507
Synonyms:US10207991, Ex. Cpd. No. 22 | US10611728, Example Compound 22 | US11691947, Example 22
TypeSmall organic molecule
Emp. Form.C18H19F2N
Mol. Mass.287.347
SMILESC[C@H](CCc1ccc(F)cc1)N1Cc2ccc(F)cc2C1 |r|
Structure
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