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TargetSigma intracellular receptor 2
LigandBDBM349513
Substrate/Competitorn/a
Meas. Tech.Competitive Radioligand Binding Assay 2
Ki 11.0±n/a nM
Citation Rishton, GMCatalano, SMLook, GC Isoindoline compositions and methods for treating neurodegenerative disease US Patent US10207991 Publication Date 2/19/2019
More Info.:Get all data from this article,  Assay Method
 
Sigma intracellular receptor 2
Name:Sigma intracellular receptor 2
Synonyms:MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:Protein
Mol. Mass.:20857.20
Organism:Homo sapiens (Human)
Description:Q5BJF2
Residue:176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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BDBM349513
n/a
NameBDBM349513
Synonyms:US10207991, Ex. Cpd. No. 28 | US10611728, Example Compound 28 | US11691947, Example 28
TypeSmall organic molecule
Emp. Form.C22H28FNO2
Mol. Mass.357.4616
SMILESCC(C)Oc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O
Structure
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