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TargetP2X2/3
LigandBDBM319931
Substrate/Competitorn/a
Meas. Tech.Intracellular Calcium Measurement to Assess Antagonist Activity
IC50 19.0±n/a nM
Citation Davenport AJBräuer NFischer OMRotgeri ARottmann ANeagoe INagel JGodinho-Coelho AKlar J 1,3-thiazol-2-yl substituted benzamides US Patent  US10202369 Publication Date 2/12/2019  Article
More Info.:Get all data from this article,  Assay Method
 
P2X2/3
Name:P2X2/3
Synonyms:n/a
Type:Protein
Mol. Mass.:n/a
Description:n/a
Components:This complex has 2 components.
BDBM319931
n/a
NameBDBM319931
Synonyms:3-(5-Methyl- 1,3-thiazol-2- yl)-5- (tetrahydro- 2H-pyran-4- ylmethoxy)- N-[(1R)-1-[2- (trifluorometh- yl)pyrimidin- 5- yl]ethyl] benzamide | US10174016, Example 98 | US10202369, Example 98
TypeSmall organic molecule
Emp. Form.C24H25F3N4O3S
Mol. Mass.506.541
SMILESC[C@@H](NC(=O)c1cc(OCC2CCOCC2)cc(c1)-c1ncc(C)s1)c1cnc(nc1)C(F)(F)F |r|
Structure
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