| Reaction Details |
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 | Report a problem with these data |
| Target | D-amino-acid oxidase |
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| Ligand | BDBM50431069 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | DAAO Inhibitory Activity Assay |
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| IC50 | 2.00±n/a nM |
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| Citation |  Hondo, T; Nakanishi, K; Niimi, T; Warizaya, M; Namatame, I; Harada, K Dihydroxy aromatic heterocyclic compound US Patent US10202399 Publication Date 2/12/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| D-amino-acid oxidase |
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| Name: | D-amino-acid oxidase |
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| Synonyms: | D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN |
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| Type: | Homodimer |
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| Mol. Mass.: | 39476.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14920 |
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| Residue: | 347 |
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| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
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| BDBM50431069 |
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| n/a |
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| Name | BDBM50431069 |
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| Synonyms: | CHEMBL2338795 | US10202399, Example 27 | US10463663, Example 7 | US11129828, Example 7 | US9212147, 27 | US9290456, 7 | US9931340, Example 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H11FN2O2 |
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| Mol. Mass. | 234.2263 |
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| SMILES | Oc1cc(CCc2ccccc2F)n[nH]c1=O |
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| Structure | 
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