| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 8 |
|---|
| Ligand | BDBM347330 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| Ki | 0.170±n/a nM |
|---|
| Citation |  Wright, DL; Anderson, AC; Van Heyst, M; Ononye, S Substituted tropolone derivatives and methods of use US Patent US9790158 Publication Date 10/17/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 8 |
|---|
| Name: | Histone deacetylase 8 |
|---|
| Synonyms: | HD8 | HDAC8 | HDAC8_HUMAN | HDACL1 | Histone deacetylase 8 (HDAC-8) | Human HDAC8 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41749.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9BY41 |
|---|
| Residue: | 377 |
|---|
| Sequence: | MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
RIQQILNYIKGNLKHVV
|
|
|
|---|
| BDBM347330 |
|---|
| n/a |
|---|
| Name | BDBM347330 |
|---|
| Synonyms: | MO-OH-PHE | US9790158, 1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H10O2 |
|---|
| Mol. Mass. | 198.2173 |
|---|
| SMILES | Oc1ccccc(-c2ccccc2)c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
