| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM349518 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| Ki | 0.530±n/a nM |
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| Citation |  Rishton, G; Catalano, SM; Look, GC Isoindoline compositions and methods for treating neurodegenerative disease US Patent US9796672 Publication Date 10/24/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20857.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q5BJF2 |
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| Residue: | 176 |
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| Sequence: | MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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| BDBM349518 |
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| n/a |
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| Name | BDBM349518 |
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| Synonyms: | US10207991, Ex. Cpd. No. 34 | US10611728, Example Compound 34 | US11691947, Example 34 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26FNO2 |
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| Mol. Mass. | 343.435 |
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| SMILES | COc1cc2CN(Cc2cc1OC)C(C)(C)CCc1ccc(F)cc1 |
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| Structure | 
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