| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 5A, mitochondrial |
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| Ligand | BDBM16663 |
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| Substrate/Competitor | BDBM10856 |
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| Meas. Tech. | Esterase Assay |
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| Ki | 103±n/a nM |
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| Citation |  Vullo, D; Franchi, M; Gallori, E; Antel, J; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides. J Med Chem47:1272-9 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Carbonic anhydrase 5A, mitochondrial |
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| Name: | Carbonic anhydrase 5A, mitochondrial |
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| Synonyms: | CAH5A_MOUSE | Ca5 | Ca5a | Car5 | Car5a | Carbonate dehydratase VA | Carbonic Anhydrase V | Carbonic Anhydrase VA | Carbonic anhydrase 5A, mitochondrial precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 34081.17 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Full length murine, cloned isozyme. |
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| Residue: | 299 |
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| Sequence: | MLRRDPRKPLAILRHVGLLCATGPQRWRFQHSCAEEHSNCARHPLWTGPVSSAEGTRQSP
INIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGYFFQVEFDDSCEDSGISGGPLGNHYRL
KQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLAVIGVFLKL
GAHHQALQKLVDVLPEVRHKDTQVAMGPFDPSCLLPACRDYWTYPGSLTTPPLAESVTWI
VQKTPVEVSPSQLSTFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFRLDRTKMRS
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| BDBM16663 |
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| BDBM10856 |
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| Name | BDBM16663 |
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| Synonyms: | N-(4-{[2-(4-sulfamoylphenyl)ethyl]sulfamoyl}phenyl)acetamide | aromatic sulfonamide compound 28 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N3O5S2 |
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| Mol. Mass. | 397.469 |
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| SMILES | CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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