| Reaction Details |
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 | Report a problem with these data |
| Target | Androgen receptor |
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| Ligand | BDBM354703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| IC50 | 10.5±n/a nM |
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| Citation |  Choi, SP; Choi, SM; Son, BH; Kim, HJ; Kim, JM; Jang, BJ; Sung, JH; Lee, JH; Kim, E; Kang, KK; Kim, S Oxazolidine-based compound and selective androgen receptor agonist comprising same US Patent US9809583 Publication Date 11/7/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Androgen receptor |
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| Name: | Androgen receptor |
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| Synonyms: | n/a |
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| Type: | n/a |
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| Mol. Mass.: | 97086.15 |
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| Organism: | Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) |
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| Description: | A0A0D9RHK8 |
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| Residue: | 900 |
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| Sequence: | MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLQQQQQQ
QQQQQQQQETSPRQQQKQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSAPECHPERGCVP
EPGAAVAAGKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQL
LQQQQQEAVSEGSSNGRAREASGAPTSSKDNYLGGTSTISDSAKELCKAVSVSMGLGVEA
LEHLSPGEQLRGDCMYAPVLGVPPGVRPIPCAPLAECKGSLLDDSAGKSTEDTVEYSPFK
GGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAG
PPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASS
SWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGAGEAGAVAPYGYTRPPQGLAGQEGDFTAP
DVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTC
LICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKC
YEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETAQKLTVSHIEGYECQPIFLNVLEA
IEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQY
SWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQI
TPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQL
TKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
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| BDBM354703 |
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| n/a |
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| Name | BDBM354703 |
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| Synonyms: | Preparation of 4-((2R,5S)-5-((4-cyano-2-fluorophenoxy)methyl)-2-(trifluoromethyl)oxazolidin-3-yl)-2-(trifluoromethyl)benzonitrile | US9809583, Example 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H12F7N3O2 |
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| Mol. Mass. | 459.317 |
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| SMILES | Fc1cc(ccc1OC[C@@H]1CN([C@H](O1)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C#N |r| |
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| Structure | 
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