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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | ||
| Ligand | BDBM355929 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Biochemical Assay | ||
| IC50 | 0.004±n/a nM | ||
| Citation |  Soldermann, CP; Quancard, J; Schlapbach, A; Simic, O; Tintelnot-Blomley, M; Zoller, T Pyrazolo pyrimidine derivatives and their use as MALT1 inhibitors US Patent US9815842 Publication Date 11/14/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | |||
| Name: | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | ||
| Synonyms: | MALT lymphoma-associated translocation | MALT lymphoma-associated translocation (MALT1) | MALT1 | MALT1_HUMAN | MLT | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | Paracaspase | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 92257.81 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q9UDY8 | ||
| Residue: | 824 | ||
| Sequence: |
| ||
| BDBM355929 | |||
| n/a | |||
| Name | BDBM355929 | ||
| Synonyms: | 1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-yl)-3-(2- chloro-7-(2- methoxyphenyl)pyra- zolo[1,5-a]pyrimidin- 6-yl)urea | US10442808, Example 53 | US9815842, Example 53 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H15Cl2N9O2 | ||
| Mol. Mass. | 496.309 | ||
| SMILES | COc1ccccc1-c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12 |(-7.9,2.55,;-6.57,1.78,;-5.23,2.55,;-5.23,4.09,;-3.9,4.86,;-2.56,4.09,;-2.56,2.55,;-3.9,1.78,;-3.9,.24,;-2.56,-.53,;-1.23,.24,;.1,-.53,;.1,-2.07,;1.44,.24,;2.77,-.53,;2.77,-2.07,;4.1,-2.84,;5.44,-2.07,;5.44,-.53,;6.77,.24,;4.1,.24,;6.77,-2.84,;6.77,-4.38,;8.24,-4.86,;9.14,-3.61,;8.24,-2.37,;-2.56,-2.07,;-3.9,-2.84,;-5.23,-2.07,;-6.7,-2.55,;-7.6,-1.3,;-9.14,-1.3,;-6.7,-.06,;-5.23,-.53,)| | ||
| Structure | 
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