| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM151605 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Monoamine Oxidase (MAO) Assay |
|---|
| IC50 | 1300±n/a nM |
|---|
| Citation |  Vankayalapati, H; Sorna, V; Warner, SL; Stephens, B; Bearss, DJ; Sharma, S Substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs as histone demethylase inhibitors US Patent US9555024 Publication Date 1/31/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 58768.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P27338 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
|
|
|
|---|
| BDBM151605 |
|---|
| n/a |
|---|
| Name | BDBM151605 |
|---|
| Synonyms: | US8987335, 1 | US9555024, 1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H12N2O3 |
|---|
| Mol. Mass. | 256.2567 |
|---|
| SMILES | Oc1ccc(cc1)C(=O)N\N=C\c1ccccc1O |
|---|
| Structure | 
|
|---|
Search and Browse
