| Reaction Details |
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 | Report a problem with these data |
| Target | Glycine--tRNA ligase |
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| Ligand | BDBM2 |
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| Substrate/Competitor | BDBM18133 |
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| Meas. Tech. | In Vitro Enzyme Activity Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 13000±6000 nM |
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| IC50 | 100000±n/a nM |
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| Citation |  Dignam, JD; Nada, S; Chaires, JB Thermodynamic characterization of the binding of nucleotides to glycyl-tRNA synthetase. Biochemistry42:5333-40 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Glycine--tRNA ligase |
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| Name: | Glycine--tRNA ligase |
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| Synonyms: | GARS_BOMMO | GlyRS | Glycine--tRNA ligase | Glycyl-tRNA synthetase | tRNA synthetase (GlyRS) |
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| Type: | Enzyme |
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| Mol. Mass.: | 76917.70 |
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| Organism: | Bombyx mori |
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| Description: | B. mori glycyltRNA synthetase was expressed in E. coli. |
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| Residue: | 680 |
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| Sequence: | MADPKIEEILAPLRANVKEQGDLVRKLKEEKAPEIDIKKAVAELKTRKKILEDKELSLAP
AEDLFDRAKMEDLIKRRFFYDQSFAIYGGITGQFDFGPMGCALKSNMIHLWKKFFILQEQ
MLEVECSILTPEPVLKASGHVERFADLMTKDIKTGECFRLDHLIKGHLEKIKSDKNTKIE
LKAEIEDILIKLDGMNADEMSALMKRFEMKSPISGNDLTPPIEFNLMFNTQIGPSGLVKG
FLRPETAQGIFVNFKRLLEFNQGRLPFAAAQIGNSFRNEISPRSGLLRVREFTMCEIEHF
CDVKEHPKFESVKNTQSLLYSADNQEQGKPADLTTIGDAVCKGIVNNETLGYFMARIHMY
MLAVGIDPKRLRFRQHMGNEMAHYACDCWDAECLSSYGWIECVGCADRSAYDLTQHTKAT
GIRLAAEKKLPAPKQIEVVEAIANNGRIGKAFKKDSQAINDTLATLDNAALEEMQKELDS
NGEYTLITARGEFKLTPSLVNVKKTQKTIHVEEIIPSVIEPSFGVGRILYCILEHNFRMR
EGDEQRTYFSLPPTVAPMKCVVLPLSGNAEFQPFVRDLSQELITVDVSHKVDDSSGSIGR
RYARTDELGVPYAVTVDFDTIKEPHTVTLRERDSMRQVRLPMADVPTVVRDLSNSKILWS
DVEQKYPKFEQQETVKGTSV
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| BDBM2 |
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| BDBM18133 |
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| Name | BDBM2 |
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| Synonyms: | ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid | ATP | Brimonidine ATP | CHEMBL14249 |
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| Type | Nucleoside or nucleotide |
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| Emp. Form. | C10H16N5O13P3 |
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| Mol. Mass. | 507.181 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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