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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Ligand | BDBM165921 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | The [3H]-methyllycaconitine binding assay | ||
| Ki | 60.0±n/a nM | ||
| Citation |  Luithle, J; Böβ, F; Erb, C; Hafner, F; Schnizler, K; Flessner, T; Van Kampen, M; Van Der Staay, F 2-heteroaryl carboxamides US Patent US10214524 Publication Date 2/26/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuronal acetylcholine receptor subunit alpha-7 | |||
| Name: | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Synonyms: | ACHA7_RAT | Acra7 | Cholinergic, Nicotinic Alpha7 | Cholinergic, Nicotinic Alpha7/5-HT3 | Chrna7 | Neuronal acetylcholine receptor | Neuronal acetylcholine receptor (alpha7 nAChR) | Neuronal acetylcholine receptor subunit alpha 7 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR alpha7) | Neuronal acetylcholine receptor subunit alpha-7 (nAChR) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 56502.44 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | Q05941 | ||
| Residue: | 502 | ||
| Sequence: |
| ||
| BDBM165921 | |||
| n/a | |||
| Name | BDBM165921 | ||
| Synonyms: | US10214524, Example 3 | US9067931, 3 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H24N2O3 | ||
| Mol. Mass. | 376.4483 | ||
| SMILES | OCc1ccc(cc1)-c1ccc2cc(oc2c1)C(=O)N[C@H]1CN2CCC1CC2 |r,wU:20.22,(9.17,.47,;8.4,1.8,;6.86,1.8,;6.09,.47,;4.55,.47,;3.78,1.8,;4.55,3.13,;6.09,3.13,;2.24,1.8,;1.47,3.13,;-.07,3.13,;-.84,1.8,;-2.34,1.48,;-2.5,-.05,;-1.1,-.68,;-.07,.47,;1.47,.47,;-3.84,-.82,;-3.84,-2.36,;-5.17,-.05,;-6.51,-.82,;-6.51,-2.36,;-7.84,-3.13,;-9.17,-2.36,;-9.17,-.82,;-7.84,-.05,;-7.07,-1.39,;-8.56,-1.78,)| | ||
| Structure | 
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