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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Ligand | BDBM165936 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | The [3H]-methyllycaconitine binding assay | ||
| Ki | 14.0±n/a nM | ||
| Citation |  Luithle, J; Böβ, F; Erb, C; Hafner, F; Schnizler, K; Flessner, T; Van Kampen, M; Van Der Staay, F 2-heteroaryl carboxamides US Patent US10214524 Publication Date 2/26/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuronal acetylcholine receptor subunit alpha-7 | |||
| Name: | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Synonyms: | ACHA7_RAT | Acra7 | Cholinergic, Nicotinic Alpha7 | Cholinergic, Nicotinic Alpha7/5-HT3 | Chrna7 | Neuronal acetylcholine receptor | Neuronal acetylcholine receptor (alpha7 nAChR) | Neuronal acetylcholine receptor subunit alpha 7 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR alpha7) | Neuronal acetylcholine receptor subunit alpha-7 (nAChR) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 56502.44 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | Q05941 | ||
| Residue: | 502 | ||
| Sequence: |
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| BDBM165936 | |||
| n/a | |||
| Name | BDBM165936 | ||
| Synonyms: | US10214524, Example 163 | US9067931, 163 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H32N4O3 | ||
| Mol. Mass. | 472.5787 | ||
| SMILES | CN1CCN(CC1)C(=O)c1cccc(c1)-c1cccc2cc(oc12)C(=O)N[C@H]1CN2CCC1CC2 |r,wU:27.30,(9.17,-5.33,;8.4,-4,;6.86,-4,;6.09,-2.67,;6.86,-1.33,;8.4,-1.33,;9.17,-2.67,;6.09,,;6.86,1.33,;4.55,,;3.78,-1.33,;2.24,-1.33,;1.47,,;2.24,1.33,;3.78,1.33,;1.47,2.67,;2.24,4,;1.47,5.33,;-.07,5.33,;-.84,4,;-2.34,3.68,;-2.5,2.15,;-1.1,1.52,;-.07,2.67,;-3.84,1.38,;-3.84,-.16,;-5.17,2.15,;-6.51,1.38,;-6.51,-.16,;-7.84,-.93,;-9.17,-.16,;-9.17,1.38,;-7.84,2.15,;-7.07,.82,;-8.63,.28,)| | ||
| Structure | 
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