| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 4 [648-1032] |
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| Ligand | BDBM243187 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HDAC4 Biochemical Assay |
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| IC50 | 12.0±n/a nM |
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| Citation |  Maillard, MC; Breccia, P; Dominguez, C; Haughan, AF; Van de Poël, A; Stott, AJ; Luckhurst, CA; Saville-Stones, EA; Wishart, G; Wall, M; Jarvis, RE Histone deacetylase inhibitors and compositions and methods of use thereof US Patent US10053434 Publication Date 8/21/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 4 [648-1032] |
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| Name: | Histone deacetylase 4 [648-1032] |
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| Synonyms: | HDAC4 | HDAC4_HUMAN | Histone deacetylase 4 | KIAA0288 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41490.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P56524[648-1032] |
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| Residue: | 385 |
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| Sequence: | TKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKAT
LEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHS
AGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQ
RLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVG
FNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYN
LSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQ
RPNANAVRSMEKVMEIHSKYWRCLQ
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| BDBM243187 |
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| n/a |
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| Name | BDBM243187 |
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| Synonyms: | 2-((R)-2-(4-(5-(Trifluoromethyl)-1,2,4- oxadiazol-3- yl)benzamido)propyl)octahydrocyclopenta [c]pyrrol-2-ium formate | US10053434, 17 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24F3N4O2 |
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| Mol. Mass. | 409.4248 |
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| SMILES | C[C@H](C[NH+]1CC2CCCC2C1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F |r| |
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| Structure | 
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