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TargetP2X purinoceptor 3
LigandBDBM244280
Substrate/Competitorn/a
Meas. Tech.Receptor Inhibition Assay
pH7.5±n/a
IC50 1.000±n/a nM
Commentsextracted
Citation Kai HTanaka SHiramatsu YNozu ANakamura K Heterocyclic ring and carbocyclic derivative US Patent  US9550763 Publication Date 1/24/2017
More Info.:Get all data from this article,  Assay Method
 
P2X purinoceptor 3
Name:P2X purinoceptor 3
Synonyms:ATP receptor | P2RX3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor
Type:Protein
Mol. Mass.:44292.02
Organism:Homo sapiens (Human)
Description:P56373
Residue:397
Sequence:
MNCISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYRCVSDS
QCGPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVETPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEE
VNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH
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  Blast E-value cutoff:
BDBM244280
n/a
NameBDBM244280
Synonyms:US9550763, Compound I-028
TypeSmall organic molecule
Emp. Form.C26H23ClN4O5
Mol. Mass.506.938
SMILESCCn1c(=O)cc(Nc2ccc(Oc3cccc(n3)C(O)=O)c(C)c2)n(Cc2ccc(Cl)cc2)c1=O
Structure
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