| Reaction Details |
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 | Report a problem with these data |
| Target | Large envelope protein |
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| Ligand | BDBM246836 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HBsAg assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 20.0±n/a nM |
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| Comments | extracted |
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| Citation |  Han, X; Jiang, M; Wang, Y; Yang, S Tetracyclic 4-oxo-pyridine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection US Patent US10053461 Publication Date 8/21/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Large envelope protein |
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| Name: | Large envelope protein |
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| Synonyms: | HBSAG_HBVD3 | S |
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| Type: | n/a |
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| Mol. Mass.: | 42772.52 |
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| Organism: | Hepatitis B virus |
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| Description: | P03138 |
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| Residue: | 389 |
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| Sequence: | MGQNLSTSNPLGFFPDHQLDPAFRANTANPDWDFNPNKDTWPDANKVGAGAFGLGFTPPH
GGLLGWSPQAQGILQTLPANPPPASTNRQSGRQPTPLSPPLRNTHPQAMQWNSTTFHQTL
QDPRVRGLYFPAGGSSSGTVNPVLTTASPLSSIFSRIGDPALNMENITSGFLGPLLVLQA
GFFLLTRILTIPQSLDSWWTSLNFLGGTTVCLGQNSQSPTSNHSPTSCPPTCPGYRWMCL
RRFIIFLFILLLCLIFLLVLLDYQGMLPVCPLIPGSSTTSTGPCRTCMTTAQGTSMYPSC
CCTKPSDGNCTCIPIPSSWAFGKFLWEWASARFSWLSLLVPFVQWFVGLSPTVWLSVIWM
MWYWGPSLYSILSPFLPLLPIFFCLWVYI
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| BDBM246836 |
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| n/a |
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| Name | BDBM246836 |
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| Synonyms: | US10053461, 27 | trans-13-chloro-12-(3-methoxypropoxy)-2-oxo-2,5a,6,7,8,9,10,10a-octahydrocyclohepta[c]pyrido[2,1-a]isoquinoline-3-carboxylic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26ClNO5 |
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| Mol. Mass. | 431.909 |
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| SMILES | COCCCOc1cc2[C@@H]3CCCCC[C@H]3n3cc(C(O)=O)c(=O)cc3-c2cc1Cl |r| |
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| Structure | 
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