| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2X purinoceptor 7 |
|---|
| Ligand | BDBM246865 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | P2X7 Radioligand Binding |
|---|
| Ki | 1.10±n/a nM |
|---|
| Citation |  Ameriks, MK; Rech, JC; Savall, BM; Wall, JL Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators US Patent US10053463 Publication Date 8/21/2018 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2X purinoceptor 7 |
|---|
| Name: | P2X purinoceptor 7 |
|---|
| Synonyms: | P2RX7_MOUSE | P2rx7 | P2x7 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 68405.16 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1473824 |
|---|
| Residue: | 595 |
|---|
| Sequence: | MPACCSWNDVLQYETNKVTRIQSTNYGTVKWVLHMIVFSYISFALVSDKLYQRKEPVISS
VHTKVKGIAEVTENVTEGGVTKLGHSIFDTADYTFPLQGNSFFVMTNYVKSEGQVQTLCP
EYPRRGAQCSSDRRCKKGWMDPQSKGIQTGRCVPYDKTRKTCEVSAWCPTEEEKEAPRPA
LLRSAENFTVLIKNNIHFPGHNYTTRNILPTMNGSCTFHKTWDPQCSIFRLGDIFQEAGE
NFTEVAVQGGIMGIEIYWDCNLDSWSHHCRPRYSFRRLDDKNTDESFVPGYNFRYAKYYK
ENNVEKRTLIKAFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLATVCIDLLINTYSS
AFCRSGVYPYCKCCEPCTVNEYYYRKKCESIMEPKPTLKYVSFVDEPHIRMVDQQLLGKS
LQVVKGQEVPRPQMDFSDLSRLSLSLHDSPLTPGQSEEIQLLHEEVAPKSGDSPSWCQCG
NCLPSRLPEQRRALEELCCRRKPGRCITTSKLFHKLVLSRDTLQLLLLYQDPLLVLGEEA
TNSRLRHRAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKTEGQYSGFKYPY
|
|
|
|---|
| BDBM246865 |
|---|
| n/a |
|---|
| Name | BDBM246865 |
|---|
| Synonyms: | 6-(trifluoromethyl)picolinohydrazide | US10053463, 16 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H6F3N3O |
|---|
| Mol. Mass. | 205.1372 |
|---|
| SMILES | NNC(=O)c1cccc(n1)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
