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TargetCannabinoid receptor 1/Mu-type opioid receptor
LigandBDBM309336
Substrate/Competitorn/a
Meas. Tech.Opioid Receptor Binding Assay
EC50 0.350±n/a nM
Citation Blumberg LCDeaver DREyerman DJWynn TA Methods for treating depressive symptoms US Patent  US10231963 Publication Date 3/19/2019  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1/Mu-type opioid receptor
Name:Cannabinoid receptor 1/Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM309336
n/a
NameBDBM309336
Synonyms:US10231963, Table B.4 | US9656961, Example 00121
TypeSmall organic molecule
Emp. Form.C31H39NO4S
Mol. Mass.521.711
SMILESCO[C@]12CC[C@@]3(CC1[C@](C)(O)CCc1cccs1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r,TLB:8:7:28.27:4.3|
Structure
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